Which statement best describes oversight of genetic modification in animals?

• A. Genetic modification can proceed without any welfare concerns.
• B. It requires enhanced welfare oversight due to welfare concerns.
• C. It operates entirely independently of regulatory bodies.
• D. It eliminates humane endpoints.

Answer: (B)

Genetic modification in animals carries potential welfare implications, including pain, distress, or health problems from unintended effects. Because of that, oversight is enhanced: studies undergo risk assessment, formal review by committees, and ongoing welfare monitoring, with requirements to refine methods and apply humane endpoints to prevent or terminate suffering. This safeguards animal welfare while allowing scientifically valuable research. The other statements ignore these safeguards, suggesting no welfare concerns, complete independence from regulators, or the elimination of humane endpoints, which do not fit how such work is governed.